This anomaly has the potential to appear not only in the liver, but the spleen as well.
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In addition, other liver damage has been linked to stanozolol, mainly in the form of liver cell tumors. In most cases, the tumors are benign or non-cancerous, but in some cases, they have become malignant.
Stanozolol appears to offer less hepatic stress than an equivalent dose of Dianabol (methandrostenolone). Studies giving 12mg of stanozolol per day for 27 weeks failed to demonstrate clinically-significant changes in markers of liver function, including serum aspartate amino-transferase, alanine amino-transferase, gamma-glutamyltransferase, bilirubin, and alkaline phosphatase. 621 Relative hepatotoxicity increases as the dosage escalates, so hepatic dysfunction should still be a concern. In rare instances, high doses (alone or in combination with other steroids) have been implicated in cases of serious life-threatening hepatotoxicity in bodybuilders. Injectable stanozolol has also been implicated in severe hepatotoxicity in an otherwise healthy bodybuilder, 622 and should not be used as an alternative medication when liver toxicity precludes oral stanozolol use.