Water based steroid nasal spray

Q. How can folliculitis be treated? A. that ^ is true, it passes by itself after couple of weeks. what you should be aware of is the causes of it , that can give you an idea how to avoid it next time:

* Use a hot tub, whirlpool, or swimming pool that is not properly treated with chlorine.
* Wear tight clothes.
* Use antibiotics or steroid cream for long periods.
* Use or work with substances that can irritate or block the follicles. Examples include makeup, cocoa butter, motor oil, tar, and creosote.
* Have an infected cut, scrape, or surgical incision. The bacteria or fungi can spread to nearby hair follicles.
* Have a disease such as diabetes or HIV that lowers your ability to fight infection.

Glucocorticoids are potent anti-inflammatories, regardless of the inflammation's cause; their primary anti-inflammatory mechanism is lipocortin-1 (annexin-1) synthesis. Lipocortin-1 both suppresses phospholipase A2 , thereby blocking eicosanoid production, and inhibits various leukocyte inflammatory events ( epithelial adhesion , emigration , chemotaxis , phagocytosis , respiratory burst , etc.). In other words, glucocorticoids not only suppress immune response, but also inhibit the two main products of inflammation, prostaglandins and leukotrienes . They inhibit prostaglandin synthesis at the level of phospholipase A2 as well as at the level of cyclooxygenase /PGE isomerase (COX-1 and COX-2), [29] the latter effect being much like that of NSAIDs , potentiating the anti-inflammatory effect.

After subcutaneous administration of 14 C-nafarelin acetate to men, 44–55% of the dose was recovered in urine and –% was recovered in feces. Approximately 3% of the administered dose appeared as unchanged nafarelin in urine. The 14C serum half-life of the metabolites was about hours. Six metabolites of nafarelin have been identified of which the major metabolite is Tyr-D(2)-Nal-Leu-Arg-Pro-Gly-NH2(5-10). The activity of the metabolites, the metabolism of nafarelin by nasal mucosa , and the pharmacoki netics of the drug in hepatically- and renally-impaired patients have not been determined.

Water based steroid nasal spray

water based steroid nasal spray

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