My preference is to prescribe a short course of oral steroid which is tapered (reduced gradually) every two days for a total of ten days. A nasal steroid spray is prescribed for long-term use. The nasal steroid sprays are not addictive and may help to maintain good airflow through the nasal passages as the oral steroid is eliminated. The patient is instructed to stop the TND within two days, allowing time for the oral steroid to take effect. If there is no history of blood pressure elevation, heart, thyroid or eye problems, an oral decongestant (. Sudafed) may also be recommended. I also recommend nasal saline rinses.
Mometasone furoate increased chromosomal aberrations in an in vitro Chinese hamster ovary-cell assay, but did not increase chromosomal aberrations in an in vitro Chinese hamster lung cell assay. Mometasone furoate was not mutagenic in the Ames test or mouse- lymphoma assay, and was not clastogenic in an in vivo mouse micronucleus assay and a rat bone marrow chromosomal aberration assay or a mouse male germ -cell chromosomal aberration assay. Mometasone furoate also did not induce unscheduled DNA synthesis in vivo in rat hepatocytes.
You may be looking for a nasal polyps treatment miracle, but conventional treatment usually starts with a nasal corticosteroid spray. It may also include a prescription to take prednisone by mouth for one week. ( 14 ) Nasonex, fluticasone, Beconase AQ, mometasone and beclamethasone are all nasal steroids that may be prescribed to treat nasal polyps. ( 15 ) Other medication, such as antihistamines and decongestants, don’t really help nasal polyps. However, your doctor may recommend antihistamines to control allergies, or antibiotics before your start on a steroid prescription if you have an infection. ( 16 )