Unlike Dianabol (another popular 17aa oral) which is effective in doses of as little as 15mg, Anapolon users generally start with 50mg/day and often lead up to 150mg/day. So when a user takes 3 Anapolon tablets, his liver is processing roughly the equivalent of 30 Dianabol tablets. This obviously is quite a lot of 17aa steroid for your liver to process, so it is pertinent a user has his liver enzymes checked regularly with a doctor. When you hear of horror stories involving liver cancer from steroid use, Anapolon is most often the culprit. For medical treatment, Syntex recommends 1-5mg/kg of bodyweight per day. This leads many patients to take as many as 8+ tabs per day, for extended periods of time. This is much more than an athlete would need and should be using, which may be why documented cases of liver cancer seem more prominent among non-athletes taking Anapolon medically. Lately, many people are speculating on how long this product will be available worldwide. Syntex has stopped production of Anapolon in the ., Oxitosona in Spain and medical use in other areas of the world seems to be declining due to the advent of newer drugs to treat conditions in which Anapolon was formerly used.
The common side effects of oxymetholone include depression, lethargy, headache, swelling, rapid weight gain, priapism , changes in skin color, urination problems, nausea , vomiting , stomach pain (if taken on an empty stomach), loss of appetite, jaundice , breast swelling in men, feeling restless or excited, insomnia , and diarrhea .  In women, side effects also include acne , changes in menstrual periods , deepened voice, hair growth on the chin or chest, male pattern baldness , enlarged clitoris , and changes in sex drive .  Because of its 17α-alkylated structure, oxymetholone is highly hepatotoxic . Long term use of the drug can cause a variety of serious ailments, including hepatitis , liver cancer , and cirrhosis ; therefore periodic liver function tests are recommended for those taking oxymetholone. 
To strengthen the anabolic properties of testosterone, more than 100 synthetic steroid derivatives have been described for human purposes. The anabolic effect promotes protein synthesis, muscle growth and erythropoiesis. In clinical practice, substances with anabolic effect are needed to overcome various catabolic states. However, none of these compounds are devoid of androgenicity. Androgenic and anabolic properties of anabolic steroids cannot be totally separated. Therefore, it is more appropriate to use the term anabolic androgenic steroids (AAS).